Comparison of Patient Age Groups in Transplantation for Myelodysplastic Syndrome
نویسندگان
چکیده
منابع مشابه
Hematopoietic stem cell transplantation for myelodysplastic syndrome.
Allogeneic hematopoietic stem cell transplantation remains the only curative option for myelodysplastic syndrome, but patients with this disease are often older and frail, and treatment-related mortality and morbidity is a major obstacle to be overcome. Treatment of MDS is likely to benefit from the major lines of investigation in the field of allogeneic transplantation, especially intervention...
متن کاملHematopoietic cell transplantation for myelodysplastic syndrome.
Although high-dose chemotherapy may cure a small subset of patients with myelodysplastic syndrome (MDS), allogeneic hematopoietic cell transplantation (HCT) is the only currently available modality that is curative in a large proportion of patients. Approximately 30% to 40% of patients with high-risk MDS and 60% to 80% of patients with low-risk MDS survive long-term in remission. Disease classi...
متن کاملAllogeneic and syngeneic marrow transplantation for myelodysplastic syndrome in patients 55 to 66 years of age.
We carried out bone marrow transplantation (BMT) in 50 patients with myelodysplastic syndrome (MDS) who were 55.3 to 66.2 years of age (median, 58.8 years). According to the criteria of the French-American-British (FAB) classification, 13 patients had refractory anemia (RA), 19 had RA with excess blasts (RAEB), 16 had RAEB in transformation or acute myelogenous leukemia (RAEB-T/AML), and 2 had ...
متن کاملRole and Timing of Hematopoietic Cell Transplantation for Myelodysplastic Syndrome
Allogeneic hematopoietic cell transplantation (HCT) is the only curative treatment for patients with myelodysplastic syndromes (MDS). Most patients with MDS are older than 60 years and age-associated morbidities limit the patients' options for curative transplant therapy. Since the development of conditioning regimens with reduced toxicity, the age limitations for HCT have waned for those patie...
متن کاملcentral nervous system vasculitis in a patient with myelodysplastic syndrome
myelodysplastic syndromes (mds) are a group of hematological disorders ranging from chronic refractory anemia to leukemia. there are some reports about association of mds with autoimmune disorders and vasculitis. in this study we describe a patient with mds and vasculitis presenting with central nervous system (cns) involvement. a clinical response to immunosuppressive therapy was also observed...
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ژورنال
عنوان ژورنال: JAMA Oncology
سال: 2020
ISSN: 2374-2437
DOI: 10.1001/jamaoncol.2019.5140